Born Margaret Hyra in 1961, Meg Ryan's first acting success came with a role on the soap opera As The World Turns from 1982 to 1984. Her big film break was in the 1986 hit Top Gun. Ryan became America's Sweetheart when she starred in a string of hit romantic comedies in the 1990s, including When Harry Met Sally (1989), Sleepless in Seattle (1993), and You've Got Mail (1998).
Actress. Born Margaret Hyra on November 19, 1961, in Fairfield, Connecticut. Ryan??s first substantial role was as Betsy Stewart Montgomery Andropoulos on the soap opera As the World Turns from 1982 to 1984. In the mid-1980s, her film career began to heat up with a part in the wildly successful 1986 military action drama Top Gun with Tom Cruise and Anthony Edwards. She then went on to co-star with Dennis Quaid in Innerspace (1987) and D.O.A. (1988). Ryan later married Quaid in 1991.
It was her portrayal of cute, funny Sally Albright in When Harry Met Sally (1989) that took her career to a new level. The box office hit led to a string of other successful romantic comedies, such as Sleepless in Seattle (1993), French Kiss (1995), and You’ve Got Mail (1998).
Most of her more dramatic efforts, such as Proof of Life (2000), In the Cut (2003), and Against the Ropes (2004), have failed to register with film audiences. In 2001, Ryan ended her ten-year marriage to Dennis Quaid. The couple has one child together??a son named Jack. While some reports indicated that her relationship led to the split, Ryan has said that the marriage was in trouble before then. She told talk show host Oprah Winfrey on her television show in 2006 that ??I should have left sooner.??
After taking a break from the spotlight, Ryan re-emerged in 2006 with the announcement of her adoption of a little girl from China. At first she named her daughter Charlotte, but soon changed it to Daisy to better fit the child's personality. During her time away from Hollywood, Ryan has been working with CARE, a charitable organization dedicated to ending poverty by helping women work together.
Ryan returned to the big screen in 2007 with In the Land of Women, a dramatic comedy. She followed this in 2008 with The Deal and along side fellow actresses Annette Bening, Debra Messing and Jada Pinkett Smith in The Women. Ryan played a high-powered attorney opposite Timothy Hutton in 2009's Serious Moonlight which only received mixed reviews and had a limited release.
From : www.biography.com